CD31 anticorps (AA 625-738) (CF®568)

N° du produit ABIN7658662

Cet anticorps Souris Monoclonal détecte spécifiquement CD31 dans WB, IHC et IHC (fp). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD31 anticorps (AA 625-738) (CF®568) (ABIN7658662)

Antigène: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD31 est conjugé à/à la CF®568

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: PECAM1-3528

Détail du produit anti-CD31 anticorps (CF®568)

Épitope: AA 625-738

Fonction: CD31 / PECAM-1 (Endothelial Cell Marker)(PECAM1/3528), CF568 conjugate

Attributs du produit: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant fragment (around aa 625-738) of human CD31 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Jurkat cells. Tonsil or Angiosarcoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur CD31

Antigène: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Autre désignation: CD31

Sujet:

Synonyms: EndoCAM, PECA1, Platelet Endothelial Cell Adhesion Molecule 1, GPIIA

Gene Symbol: PECAM1

Tissue Expression: Endothelial cells

Poids moléculaire: ~100 kDa (endothelium) and ~130 kDa (platelets)

ID gène: 5175

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization