Prostate Specific Antigen anticorps (CF®405S)
Aperçu rapide pour Prostate Specific Antigen anticorps (CF®405S) (ABIN7659240)
Antigène
Voir toutes Prostate Specific Antigen (PSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Prostate Specific Antigen (PSA)(3E6), CF405S conjugate
-
Attributs du produit
- Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
Immunogène
- Human Prostate Specific Antigen (PSA)
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
Positive Control: PC12 cells. Normal prostate or prostate carcinoma.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.1 mg/mL
-
Buffer
- PBS, 0.1 % BSA, 0.05 % azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Protect from light
-
Stock
- 4 °C
-
Stockage commentaire
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
Date de péremption
- 24 months
-
-
- Prostate Specific Antigen (PSA)
-
Autre désignation
- Prostate Specific Antigen
-
Sujet
-
Synonyms: Antigen, prostate-specific (APS), Gamma-seminoprotein, hK3, Kallikrein related peptidase 3, Kallikrein-3 (KLK3), KLK2A1, P-30 antigen, Semenogelase, Seminin
Gene Symbol: KLK3
Tissue Expression: Prostate
-
Poids moléculaire
- 33-34 kDa
-
ID gène
- 354
-
UniProt
- P07288
-
Pathways
- Système du Complément
Antigène
-