SELPLG anticorps
Aperçu rapide pour SELPLG anticorps (ABIN7659765)
Antigène
Voir toutes SELPLG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- CD162 (Selectin P Ligand)(PSGL1/1567)
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Attributs du produit
- CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant human SELPLG (CD162) protein
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Isotype
- IgM, kappa
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Indications d'application
- For coating for ELISA, order Ab without BSA. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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Commentaires
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Positive Control: Jurkat cells. Tonsil.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, no BSA, no azide
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Agent conservateur
- Without preservative
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Stock
- -20 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- SELPLG (Selectin P Ligand (SELPLG))
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Autre désignation
- CD162
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Sujet
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Synonyms: CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein ligand 1, PSGL1, Selectin P ligand, SELPLG
Gene Symbol: SELPLG
Tissue Expression: Myeloid cells|T-cells
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Poids moléculaire
- 43-120 kDa
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ID gène
- 6404
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UniProt
- Q14242
Antigène
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