Recombinant TCL1A anticorps (AA 2-109) (CF®647)

N° du produit ABIN7660562

L’anticorps Lapin Monoclonal anti-TCL1A a été validé pour IHC et IHC (fp). Il convient pour détecter TCL1A dans des échantillons de Humain.

Aperçu rapide pour Recombinant TCL1A anticorps (AA 2-109) (CF®647) (ABIN7660562)

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TCL1A est conjugé à/à la CF®647

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: TCL1-2747R

Détail du produit anti-TCL1A anticorps (CF®647)

Épitope: AA 2-109

Fonction: TCL1 (T-Cell Marker) (TCL1/2747R), CF647 conjugate

Attributs du produit: T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human TCL1 protein fragment (around aa 2-109)

Isotype: IgG

Information d'application

Indications d'application: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

Commentaires:

Positive Control: Ramos or Raji cells. Tonsil or T-cell Lymphoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur TCL1A

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Autre désignation: TCL1

Sujet:

Synonyms: TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL1, P14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A,T-cell leukemia/lymphoma 1A, TCL1, TCL1A

Gene Symbol: TCL1A

Poids moléculaire: 14 kDa

ID gène: 10232

UniProt: P56279

Pathways: Stem Cell Maintenance