Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
5 μL/tests
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
Conseil sur la manipulation
Please protected from prolonged exposure to light and do not freeze.
Stock
4 °C
Stockage commentaire
This product can be stored at 2-8°C for 12 months.
Date de péremption
12 months
Antigène
ITGA4
(Integrin alpha 4 (ITGA4))
Autre désignation
LPAM-1
Sujet
α4β7 Integrin,CD49d/β7,LPAM-1,ITGA4,ITGB7,DATK32 antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.