Ubiquitin anticorps

N° du produit ABIN7670506

Cet anticorps anti-Ubiquitin est un anticorps Lapin Polyclonal détectant Ubiquitin dans IHC et IF. Adapté pour Humain et Rat.

Aperçu rapide pour Ubiquitin anticorps (ABIN7670506)

Antigène: Ubiquitin (Ub)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ubiquitin est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Ubiquitin anticorps

Fonction: Ubiquitin Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human Ubiquitin protein expressed by E.coli

Isotype: IgG

Information d'application

Indications d'application: IF 1:100-1:200,IHC 1:200-1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Ubiquitin

Antigène: Ubiquitin (Ub)

Autre désignation: Ubiquitin

Sujet: HEL-S-50,ubiquitin B,HEL-S,UBB,HEL-S-50,ubiquitin B,Polyubiquitin-B,Ubiquitin,This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

UniProt: P0CG47

Pathways: Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway