Cadherin 5 anticorps

N° du produit ABIN7670546

Cet anticorps Lapin Polyclonal détecte spécifiquement Cadherin 5 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Cadherin 5 anticorps (ABIN7670546)

Antigène: Cadherin 5 (CDH5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 5 est non-conjugé

Application: ELISA

Détail du produit anti-Cadherin 5 anticorps

Fonction: VE-Cadherin Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human VE-Cadherin protein expressed by E.coli

Isotype: IgG

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: VE-Cadherin

Sujet: CDH5,CD144,Cadherin-5,7B4 antigen,VascuLar endotheLiaL cadherin (VE-cadherin),Cadherins are calcium-dependent cell adhesion proteins.They preferentially interact with themselves in a homophilic manner in connecting cells,cadherins may thus contribute to the sorting of heterogeneous cell types.This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.It associates with alpha-catenin forming a link to the cytoskeleton.Acts in concert with KRIT1 and PAlS1 to establish and maintain correct endothelial cell polarity and vascular lumen.These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B.Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ,PARD3,TIAM1 and RAP1B to the cell junction.

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2