M-CSF/CSF1 anticorps

N° du produit ABIN7670577

L’anticorps Lapin Polyclonal anti-M-CSF/CSF1 a été validé pour ELISA. Il convient pour détecter M-CSF/CSF1 dans des échantillons de Humain.

Aperçu rapide pour M-CSF/CSF1 anticorps (ABIN7670577)

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp M-CSF/CSF1 est non-conjugé

Application: ELISA

Détail du produit anti-M-CSF/CSF1 anticorps

Fonction: M-CSF Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human M-CSF protein expressed by E.coli

Isotype: IgG

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur M-CSF/CSF1

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: M-CSF

Sujet: M-CSF,CSF1,CSF-1,Macrophage colony-stimulating factor 1,also known as CSF-1,M-CSF,Lanimostim and CSF1,is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production,differentiation,and function of 2 related white cell populations of the blood,the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival,monocyte-to-macrophage conversion,and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer,and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses,bone metabolism,lipoproteins clearance,fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage,but also by regulating endothelial cell chemokine expression.

UniProt: P09603

Pathways: Signalisation RTK