EPO anticorps
Aperçu rapide pour EPO anticorps (ABIN7670597)
Antigène
Voir toutes EPO AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Erythropoietin/EPO Monoclonal Antibody(Detector)
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Purification
- Protein A/G Purification
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Immunogène
- Recombinant Mouse Erythropoietin/EPO protein expressed by E.coli
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Isotype
- IgM
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Indications d'application
- ELISA Detector 0.1-0.4 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Sterile PBS , pH 7.4
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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Date de péremption
- 12 months
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- EPO (Erythropoietin (EPO))
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Autre désignation
- Erythropoietin/EPO
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Classe de substances
- Hormone
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Sujet
- MGC,ECYT,MVCD,Hematopoietin,Hemopoietin,ECYT5,EP,epoetin,Erythropoietin,MGC138142,MVCD2,Epo,This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies.
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UniProt
- P07321
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Pathways
- Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
Antigène
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