HMOX1 anticorps

N° du produit ABIN7670621

Cet anticorps Lapin Polyclonal détecte spécifiquement HMOX1 dans WB, IHC et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour HMOX1 anticorps (ABIN7670621)

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMOX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-HMOX1 anticorps

Fonction: HO1/HMOX1 Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human HO1/HMOX1 protein expressed by E.coli

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:500-1:1000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur HMOX1

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Autre désignation: HO1/HMOX1

Sujet: Heme oxygenase 1,HO-1,HMOX1,HO,HO1,EC:1.14.14.18,Heme Oxygenase (HO),also known as HMOX,is the rate limiting enzyme in the breakdown of heme into Biliverdin,CO,and iron. There are two major isoforms of this enzyme,HO-1 and HO-2. Both have similar enzymatic activity,however,HO-1 is rapidly inducible,while HO-2 is constitutively expressed. Inducers of HO-1 include cell stressors such as oxidative stress,infection,hypoxia,and cytotoxic agents. The reaction products generated by HO-1 activity are biologically active,and the enzyme has a broad range of putative roles. For instance,Biliverdin is an antioxidant with cytoprotective and anti-inflammatory properties,and CO has the potential to suppress inflammation and apoptosis. Because of these activities,HO-1 has received much attention as a therapeutic target for a range of pathological processes.

Poids moléculaire:

Calculated MW: 33kDa

ObservedMW: 25kDa

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome