IFNA1 anticorps

N° du produit ABIN7670652

L’anticorps Rat Monoclonal anti-IFNA1 a été validé pour ELISA (Capture). Il convient pour détecter IFNA1 dans des échantillons de Souris.

Aperçu rapide pour IFNA1 anticorps (ABIN7670652)

Antigène: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA1 est non-conjugé

Application: ELISA (Capture)

Clone: 7B2

Détail du produit anti-IFNA1 anticorps

Fonction: IFN-alpha 1 Monoclonal Antibody(Capture)

Purification: Protein A/G Purification

Immunogène: Recombinant Mouse IFN-alpha 1 protein expressed by Mammalian

Isotype: IgG2a

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur IFNA1

Antigène: IFNA1 (Interferon, alpha 1 (IFNA1))

Autre désignation: IFN-alpha 1

Sujet: Ifna,IL-1ra Homolog,IFN-α,IL-1F,IL-1L,IL-1HY,IL-1RP,IFN-alpha,FIL1 delta,IFN-alpha-1,IFN-α1,IL-1 delta,IL-1F5,IL-1HY1,IL-1L1,IL-1ra Homolog 1,IL-1RP3,Ifna1,The interferons (IFN) are a family of cytokines with potent antiviral, antiproliferative and immunomodulatory properties, and classified based on their binding specificity to cell surface receptors. The type I IFN bind to the interferon alpha receptor (IFNAR), which consists of two subunits: IFNAR1 ( alpha -subunit) and IFNAR2 ( beta -subunit). This binding contributes to TNF-alpha induced signaling. Both the human and mouse genome code for more than a dozen closely related IFNa subtypes and the varous IFN a share about 80 % sequence homology among them. Interferon-alpha 1 (IFNA1) is a secreted, approximately 19 kDa member of the type I interferon family of molecules. Mature mouse IFN-alpha 1 shares 63 % and 82 % amino acid sequence identity with human and rat IFN-alpha 1, respectively. Low level IFN-alpha is detected under physiological conditions, and the production of IFNs is markedly enhanced during virus infection. Although originally discovered by its capability to fight virus replication, IFN-alpha functions as a prototypic tumor suppressor that represses the clinical tumorigenic phenotype in some malignancies.

UniProt: P01572

Pathways: Signalistation JAK/STAT, Hepatitis C