IL-18 anticorps

N° du produit ABIN7670661

L’anticorps anti-IL-18 Polyclonal produit chez le Lapin a été validé pour ELISA. Il convient pour la détection de IL-18 dans des échantillons provenant de Humain. }

Aperçu rapide pour IL-18 anticorps (ABIN7670661)

Antigène: IL-18 (IL18) (Interleukin 18 (IL18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-18 est non-conjugé

Application: ELISA

Détail du produit anti-IL-18 anticorps

Fonction: IL-18/IL-1F4 Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human IL-18/IL-1F4 protein expressed by E.coli

Isotype: IgG

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur IL-18

Antigène: IL-18 (IL18) (Interleukin 18 (IL18))

Autre désignation: IL-18/IL-1F4

Sujet: IL18,IL-18, IGIF, IL1F4,Iboctadekin,Interferon gamma-inducing factor,InterLeukin-1 gamma (IL-1 gamma),Pro-inflammatory cytokine primarily involved in epithelial barrier repair,polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.Upon binding to Il18R1 and Il18RAP,forms a signaling ternary complex which activates NF-kappa-B,triggering synthesis of inflammatory mediators.Synergizes with Il12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

UniProt: Q14116

Pathways: Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome