PAI1 anticorps

N° du produit ABIN7670717

Cet anticorps Lapin Polyclonal détecte spécifiquement PAI1 dans WB et ELISA. Il présente une réactivité envers Rat.

Aperçu rapide pour PAI1 anticorps (ABIN7670717)

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PAI1 anticorps

Fonction: Serpin E1/PAI-1 Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogène: Recombinant Rat Serpin E1/PAI-1 protein expressed by Mammalian

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur PAI1

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Autre désignation: Serpin E1/PAI-1

Sujet: PLasminogen activator inhibitor 1,PAI-1,EndotheLiaL pLasminogen activator inhibitor,Serpin E1,SERPINE1,PLANH1,Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PlAT) and urokinase-type plasminogen activator (PlAU). As PlAT inhibitor,it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PlAU inhibitor,it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration,independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells,and regulates odontoblast differentiation and dentin formation during odontogenesis.

Poids moléculaire:

Calculated MW: 45 kDa

ObservedMW: 47 kDa

UniProt: P20961

Pathways: Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration