Fc gamma RII (CD32) anticorps (APC)

N° du produit ABIN7672707

L’anticorps Souris Monoclonal anti- a été validé pour FACS. Il convient pour détecter dans des échantillons de Humain.

Aperçu rapide pour Fc gamma RII (CD32) anticorps (APC) (ABIN7672707)

Antigène: Fc gamma RII (CD32)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: APC

Application: Flow Cytometry (FACS)

Clone: IV-3

Détail du produit

Fonction: APC Anti-Human CD32 Antibody

Purification: 0

Pureté: 0

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détail du antigène

Antigène: Fc gamma RII (CD32)

Autre désignation: CD32

Sujet:

Synonyms: IGFR2|CD32|CDw32|FCG2|FCGR2B|Fc-gamma RII-b|Fc-gamma-RIIb|FcRII-b|IgG Fc receptor II-b|Low affinity immunoglobulin gamma Fc region receptor II-b

Background: CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Poids moléculaire: 0

ID gène: 2212

UniProt: P31994