IL2 Receptor beta anticorps (APC)

N° du produit ABIN7672796

Cet anticorps Rat Monoclonal détecte spécifiquement IL2 Receptor beta dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour IL2 Receptor beta anticorps (APC) (ABIN7672796)

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL2 Receptor beta est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: 5H4

Détail du produit anti-IL2 Receptor beta anticorps (APC)

Fonction: APC Anti-Mouse CD122/IL-2RB Antibody

Purification: 0

Pureté: 0

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur IL2 Receptor beta

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Autre désignation: CD122

Sujet:

Synonyms: IL-2R subunit beta|CD122|High affinity IL-2 receptor subunit beta|IL-2 receptor subunit beta|IL-2RB|Il2rb|Interleukin-2 receptor subunit beta|p70-75

Background: CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Poids moléculaire: 0

ID gène: 16185

UniProt: P16297

Pathways: Signalistation JAK/STAT, Growth Factor Binding