Cyclin E2 anticorps

N° du produit ABIN7672945

Cet anticorps anti-Cyclin E2 est un anticorps Lapin Polyclonal détectant Cyclin E2 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Cyclin E2 anticorps (ABIN7672945)

Antigène: Cyclin E2 (CCNE2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin E2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-Cyclin E2 anticorps

Fonction: CCNE2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: G1/S-specific cyclin-E2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Cyclin E2

Antigène: Cyclin E2 (CCNE2)

Autre désignation: CCNE2

Sujet:

Synonyms: G1/S-specific cyclin-E2|CCNE2

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.

Poids moléculaire: 44 kDa

ID gène: 9134

UniProt: O96020

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases