GSDMD anticorps (AA 276-484)

N° du produit ABIN7673340

L’anticorps Souris Monoclonal anti-GSDMD a été validé pour WB, ELISA et IF. Il convient pour détecter GSDMD dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GSDMD anticorps (AA 276-484) (ABIN7673340)

Antigène: GSDMD (Gasdermin D (GSDMD))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GSDMD est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 10D7

Détail du produit anti-GSDMD anticorps

Épitope: AA 276-484

Fonction: GSDMD antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 276-484aa

Immunogen: gasdermin D

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:1000-1:5000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur GSDMD

Antigène: GSDMD (Gasdermin D (GSDMD))

Autre désignation: GSDMD

Sujet:

Synonyms: Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D, C-terminal (GSDMD-CT, hGSDMD-CTD)|Gasdermin-D, p13|Gasdermin-D, 13 kDa (13 kDa GSDMD)|Gasdermin-D, p40|GSDMD|DFNA5L|GSDMDC1

Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Poids moléculaire: 47-53 kDa

ID gène: 79792

UniProt: P57764

Pathways: Inflammasome