Non-Syndromic Hearing Impairment Protein 5 (GSDME) anticorps

N° du produit ABIN7673342

Cet anticorps Souris Monoclonal détecte spécifiquement dans ELISA et WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Non-Syndromic Hearing Impairment Protein 5 (GSDME) anticorps (ABIN7673342)

Antigène: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Clone: 8A1

Détail du produit

Fonction: GSDME antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen: deafness, autosomal dominant 5

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détail du antigène

Antigène: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Autre désignation: GSDME

Sujet:

Synonyms: Gasdermin-E|Inversely correlated with estrogen receptor expression 1 (ICERE-1)|Non-syndromic hearing impairment protein 5|Gasdermin-E, N-terminal (GSDME-NT)|Gasdermin-E, C-terminal (GSDME-CT)|GSDME|DFNA5|ICERE1

Background: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 50-55 kDa

ID gène: 1687

UniProt: O60443