ULK1 anticorps (pSer556)

N° du produit ABIN7674408

L’anticorps Lapin Monoclonal anti-ULK1 a été validé pour WB. Il convient pour détecter ULK1 dans des échantillons de Humain.

Aperçu rapide pour ULK1 anticorps (pSer556) (ABIN7674408)

Antigène: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ULK1 est non-conjugé

Application: Western Blotting (WB)

Clone: 0

Détail du produit anti-ULK1 anticorps

Épitope: pSer556

Fonction: Phospho-ULK1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: Peptide

Immunogen: peptide

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur ULK1

Antigène: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Autre désignation: ULK1ULK1

Sujet:

Synonyms: Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog (ATG1, hATG1)|Unc-51-like kinase 1|ULK1|KIAA0722

Background: ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).

Poids moléculaire: 140-150 kDa

ID gène: 8408

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagy