ITGA4 anticorps (FineTest®647)

N° du produit ABIN7675139

Cet anticorps anti-ITGA4 est un anticorps Souris Monoclonal détectant ITGA4 dans FACS. Adapté pour Humain.

Aperçu rapide pour ITGA4 anticorps (FineTest®647) (ABIN7675139)

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA4 est conjugé à/à la FineTest®647

Application: Flow Cytometry (FACS)

Clone: 9F10

Détail du produit anti-ITGA4 anticorps (FineTest®647)

Fonction: FineTest®647 Anti-Human CD49d Antibody

Isotype: IgG1, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur ITGA4

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Autre désignation: CD49d

Sujet:

Synonyms: CD49 antigen-like family member D|CD49d|ITGA4|Integrin alpha-4|Integrin alpha-IV|VLA-4 subunit alpha

Background: CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

Poids moléculaire: 0

ID gène: 3676

UniProt: P13612

Pathways: Integrin Complex