CCR3 anticorps (FineTest®Violet 450)
Aperçu rapide pour CCR3 anticorps (FineTest®Violet 450) (ABIN7675395)
Antigène
Voir toutes CCR3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- FineTest®Violet 450 Anti-Human CD193/CCR3 Antibody
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Isotype
- IgG2b, kappa
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Indications d'application
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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Commentaires
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FineTest®Violet Dyes are designed to be excited by the violet laser at 405 nm
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Date de péremption
- 12 months
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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Autre désignation
- CD193
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Sujet
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Synonyms: MIP1-alpha receptor like-2eotaxin receptor|C-C chemokine receptor type 3|CC CKR3|CCR|CCR3
Background: CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
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Poids moléculaire
- 0
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ID gène
- 1232
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UniProt
- P51677
Antigène
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