SELPLG anticorps (FineTest®Violet 450)

N° du produit ABIN7675467

Cet anticorps Rat Monoclonal détecte spécifiquement SELPLG dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour SELPLG anticorps (FineTest®Violet 450) (ABIN7675467)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp SELPLG est conjugé à/à la FineTest®Violet 450

Application: Flow Cytometry (FACS)

Clone: 4RA10

Détail du produit anti-SELPLG anticorps (FineTest®Violet 450)

Fonction: FineTest®Violet 450 Anti-Mouse CD162 Antibody

Isotype: IgG1, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

FineTest®Violet Dyes are designed to be excited by the violet laser at 405 nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: CD162

Sujet:

Synonyms: CD162|P-selectin glycoprotein ligand 1|PSGL-1|Selectin P ligand|Selplg|PSGL1

Background: The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.

Poids moléculaire: 0

ID gène: 20345

UniProt: Q62170