SLAMF1 anticorps (FineTest®700)
Aperçu rapide pour SLAMF1 anticorps (FineTest®700) (ABIN7675523)
Antigène
Voir toutes SLAMF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- FineTest®700 Anti-Mouse CD150/SLAM Antibody
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Isotype
- IgG2a, lambda
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Indications d'application
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Date de péremption
- 12 months
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- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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Autre désignation
- CD150
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Sujet
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Synonyms: CD 150|Signaling lymphocytic activation molecule|Slam|Slamf1
Background: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.
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Poids moléculaire
- 0
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ID gène
- 27218
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UniProt
- Q9QUM4
Antigène
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