Transferrin Receptor anticorps (AA 21-120)

N° du produit ABIN734378

L’anticorps Lapin Polyclonal anti-Transferrin Receptor a été validé pour FACS et ELISA. Il convient pour détecter Transferrin Receptor dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour Transferrin Receptor anticorps (AA 21-120) (ABIN734378)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Détail du produit anti-Transferrin Receptor anticorps

Épitope: AA 21-120

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Transferrin receptor

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Transferrin Receptor (ABIN734378)

Gao, Bai, Wang, Sun, Guan, Zheng: "All-trans retinoic acid promotes nerve cell differentiation of yolk sac-derived mesenchymal stem cells." dans: Applied biochemistry and biotechnology, Vol. 174, Issue 2, pp. 682-92, (2014) (PubMed).

Gao, Bai, Xiong, Li, Shan, Huang, Ma, Guan: "Isolation and characterization of chicken dermis-derived mesenchymal stem/progenitor cells." dans: BioMed research international, Vol. 2013, pp. 626258, (2013) (PubMed).

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: Transferrin receptor

Sujet:

Synonyms: Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, TFRC

Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Poids moléculaire: 95kDa

ID gène: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis