Recombinant IL-6R (Tocilizumab Biosimilar) anticorps

N° du produit ABIN7795095

L’anticorps anti-IL-6R (Tocilizumab Biosimilar) Monoclonal Humanized est utilisé pour la détection de IL-6R (Tocilizumab Biosimilar) dans des échantillons de Humain. Il a été validé pour FACS et in vivo.

Aperçu rapide pour Recombinant IL-6R (Tocilizumab Biosimilar) anticorps (ABIN7795095)

Antigène: IL-6R (Tocilizumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Humanized

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6R (Tocilizumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité: Research Grade

Détail du produit anti-IL-6R (Tocilizumab Biosimilar) anticorps

Expression System: Mammalian cells

Fonction: Tocilizumab Biosimilar, Human IL-6R Monoclonal Antibody

Attributs du produit: What is tocilizumab biosimilar research grade? Tocilizumab biosimilar uses the same protein sequences as the therapeutic antibody tocilizumab. Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. Interleukin 6 (IL-6) is a pro-inflammatory cytokine produced by cells including T-cells, B-cells, lymphocytes, monocytes, fibroblasts. IL-6 rapidly induces C-reactive protein, serum amyloid A, fibrinogen, haptoglobin, and α-1-antichymotrypsin while inhibiting production of fibronectin, albumin, and transferrin. IL-6 also induces antibody production, induces cytotoxic T-cell differentiation, and inhibits regulatory T-cell differentiation. Tocilizumab binds soluble and membrane bound IL-6 receptors, preventing IL-6 mediated inflammation.

Purification: Protein A or G affinity column

Pureté: >95 % by reducing SDS-PAGE

niveau d'endotoxine: < 1 EU per 1 mg of the protein by the LAL method

Immunogène: Human IL-6R

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: > 3 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Détails sur IL-6R (Tocilizumab Biosimilar)

Antigène: IL-6R (Tocilizumab Biosimilar)

Autre désignation: Tocilizumab Biosimilar

Classe de substances: Biosimilar