Recombinant CTLA4 anticorps
Aperçu rapide pour Recombinant CTLA4 anticorps (ABIN7795354)
Antigène
Voir toutes CTLA4 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Expression System
- Mammalian cells
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Fonction
- In vivo Grade Recombinant Anti-mouse CTLA-4 Monoclonal Antibody, Mouse IgG2c-L234A L235A P329G (LALAPG) Kappa (Clone: 9D9)
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Attributs du produit
- The 9D9 antibody blocks the mouse cytotoxic T lymphocyte antigen-4 (CTLA-4). Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is an inhibitory molecule that competes with the stimulatory CD28 for binding to B7 on antigen presenting cells. CTLA-4 and CD28 are both presented on the surface of T-cells.
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Purification
- Protein A or G affinity column
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Pureté
- >95 % by reducing SDS-PAGE
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niveau d'endotoxine
- < 1 EU per 1 mg of the protein by the LAL method
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Isotype
- IgG2c, L234A, L235A, P329G
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Autre désignation
- CTLA-4
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Pathways
- Cancer Immune Checkpoints
Antigène
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