Recombinant CD8 alpha anticorps

N° du produit ABIN7795494

L’anticorps Human Monoclonal anti-CD8 alpha a été validé pour FACS. Il convient pour détecter CD8 alpha dans des échantillons de Souris.

Aperçu rapide pour Recombinant CD8 alpha anticorps (ABIN7795494)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 alpha est non-conjugé

Application: Flow Cytometry (FACS)

Clone: YTS 105-18

Détail du produit anti-CD8 alpha anticorps

Expression System: Mammalian cells

Fonction: Recombinant Anti-mouse CD8a Monoclonal Antibody (Clone: YTS 105.18), Human IgG1 Fc Silent Kappa

Attributs du produit: The rat anti-mouse CD8a monoclonal antibody YTS 105.18 (rat IgG2b kappa) reacts with the mouse CD8a protein (T-cell surface glycoprotein CD8 alpha chain) encoded by the mouse CD8A gene that encodes the CD8a chain of the dimeric CD8 protein. The mouse CD8 protein is primarily responsible for cell-mediated immune defense and T-cell development. CD8A has been widely reported as a potential prognosis and diagnostic marker for several diseases, such as inflammatory disorders and tumors. YTS 105.18 is a rat IgG2b anti-CD8a monoclonal antibody that does not deplete CD8+ T-cells in vivo and is widely used for the blockade of CD8+ T-cell activity in mice. Inoculation of mice with YTS 105.18 induces tolerance to zenograft transplantation and reduces insulin-dependent diabetes mellitus (IDDM) in NOD mice. Some suppliers and researchers state that YTS 105.18 is a rat IgG2a monoclonal antibody. Its sequence of the heavy chain indicates that it is a rat IgG2b antibody. Our recombinant YTS 105.18 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse CD8a monoclonal antibody (hybridoma clone name or number: YTS 105.18).

Purification: Protein A or G affinity column

Pureté: >95 % by reducing SDS-PAGE

Isotype: Fc Silenced, IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: > 3 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8a

Pathways: TCR Signaling