Recombinant BLM anticorps (C-Term)

N° du produit ABIN7795726

Cet anticorps anti-BLM est un anticorps Lapin Monoclonal détectant BLM dans IHC et ICC. Adapté pour Humain et Souris.

Aperçu rapide pour Recombinant BLM anticorps (C-Term) (ABIN7795726)

Antigène: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp BLM est non-conjugé

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR313M

Détail du produit anti-BLM anticorps

Épitope: C-Term

Fonction: Rabbit anti-BLM Recombinant Monoclonal Antibody [BLR313M]

Purification: Purified

Immunogène: Between 1367 and C-terminus

Isotype: IgG

Information d'application

Indications d'application: ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval using pressure cooker with citrate buffer pH 6.0 is recommended for FFPE cell sections.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur BLM

Antigène: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Autre désignation: BLM

Sujet: Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.

ID gène: 641

UniProt: P54132

Pathways: Réparation de l'ADN