Recombinant Neurofibromin 1 anticorps (C-Term)

N° du produit ABIN7795776

L’anticorps Lapin Monoclonal anti-Neurofibromin 1 a été validé pour WB, IP et FACS. Il convient pour détecter Neurofibromin 1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant Neurofibromin 1 anticorps (C-Term) (ABIN7795776)

Antigène: Neurofibromin 1 (NF1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Neurofibromin 1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: BLR345M

Détail du produit anti-Neurofibromin 1 anticorps

Épitope: C-Term

Fonction: Rabbit anti-Neurofibromin 1 Recombinant Monoclonal Antibody [BLR345M] - BSA-Free

Purification: Purified

Immunogène: between 2789 and 2839 (C-term)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur Neurofibromin 1

Antigène: Neurofibromin 1 (NF1)

Autre désignation: Neurofibromin 1

Sujet: Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.

ID gène: 4763

UniProt: P21359

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity