Recombinant Topoisomerase II alpha anticorps (AA 650-700)

N° du produit ABIN7795794

L’anticorps anti-Topoisomerase II alpha Monoclonal Lapin est utilisé pour la détection de Topoisomerase II alpha dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC et ICC.

Aperçu rapide pour Recombinant Topoisomerase II alpha anticorps (AA 650-700) (ABIN7795794)

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Topoisomerase II alpha est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR358N

Détail du produit anti-Topoisomerase II alpha anticorps

Épitope: AA 650-700

Fonction: Rabbit anti-Topo II Alpha Recombinant Monoclonal Antibody [BLR358N]

Purification: Purified

Immunogène: between 650 and 700

Isotype: IgG

Information d'application

Indications d'application: ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 500 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur Topoisomerase II alpha

Antigène: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Autre désignation: Topo II Alpha

Sujet: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.

ID gène: 7153

UniProt: P11388

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases