Recombinant RPA2 anticorps (pSer33)

N° du produit ABIN7795804

Cet anticorps anti-RPA2 est un anticorps Lapin Monoclonal détectant RPA2 dans ICC. Adapté pour Humain.

Aperçu rapide pour Recombinant RPA2 anticorps (pSer33) (ABIN7795804)

Antigène: RPA2 (Replication Protein A2, 32kDa (RPA2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RPA2 est non-conjugé

Application: Immunocytochemistry (ICC)

Clone: BLR364N

Détail du produit anti-RPA2 anticorps

Épitope: pSer33

Fonction: Rabbit anti-Phospho RPA32 (S33) Recombinant Monoclonal Antibody [BLR364N]

Purification: Purified

Immunogène: surrounding Serine 33

Isotype: IgG

Information d'application

Indications d'application: ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur RPA2

Antigène: RPA2 (Replication Protein A2, 32kDa (RPA2))

Autre désignation: RPA32

Sujet: Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32 kDa (RPA2), and 14 kDa (RPA3). RPA2, the 32 kDa subunit, is phosphorylated by the cdc2 family of kinases when cells enter S-phase and in response to DNA damage by ATM, ATR, and DNA-PK.

ID gène: 6118

UniProt: P15927

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA