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Histone 3 anticorps (AA 71-136)

L’anticorps Lapin Polyclonal anti-Histone 3 a été validé pour WB, ELISA, ICC, IHC (p), FACS, IF (cc), IF (p) et IHC (fro). Il convient pour détecter Histone 3 dans des échantillons de Humain, Souris et Rat. Il y a 13+ publications disponibles.
N° du produit ABIN739109

Aperçu rapide pour Histone 3 anticorps (AA 71-136) (ABIN739109)

Antigène

Voir toutes Histone 3 (H3) Anticorps
Histone 3 (H3) (Histone H3 (H3))

Reactivité

  • 1442
  • 940
  • 841
  • 39
  • 39
  • 37
  • 34
  • 33
  • 25
  • 23
  • 20
  • 20
  • 11
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 1223
  • 245
  • 12
  • 5
Lapin

Clonalité

  • 1122
  • 362
  • 1
Polyclonal

Conjugué

  • 866
  • 79
  • 47
  • 46
  • 44
  • 44
  • 44
  • 44
  • 29
  • 27
  • 18
  • 18
  • 18
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  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 7
  • 1
Cet anticorp Histone 3 est non-conjugé

Application

  • 1083
  • 392
  • 392
  • 340
  • 248
  • 191
  • 187
  • 173
  • 163
  • 162
  • 145
  • 129
  • 114
  • 48
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  • 37
  • 35
  • 26
  • 25
  • 15
  • 14
  • 7
  • 7
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    • 54
    • 51
    • 49
    • 45
    • 42
    • 42
    • 40
    • 38
    • 36
    • 36
    • 36
    • 34
    • 32
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    • 26
    • 24
    • 23
    • 22
    • 19
    • 19
    • 18
    • 18
    • 18
    • 17
    • 17
    • 15
    • 15
    • 15
    • 15
    • 15
    • 14
    • 14
    • 13
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 11
    • 10
    • 10
    • 9
    • 9
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    • 8
    AA 71-136

     Réactivité croisée

    Humain, Souris, Rat

    Homologie

    Cow,Pig,Rabbit,Drosophila

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from human Histone H3

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • Si, Meng, Gao, Hui, Li, Liu, Yang: "Linagliptin protects rat carotid artery from balloon injury and activates the NRF2 antioxidant pathway." dans: Experimental animals, Vol. 68, Issue 1, pp. 81-90, (2019) (PubMed).

    Zhang, Zhang, Li, Wang, Gu, Feng, Wei, Peng, Zhang, Su, Wang, Li, Yang, Wong, Yang, Ma: "Uncoupling Protein 2 Inhibits Myointimal Hyperplasia in Preclinical Animal Models of Vascular Injury." dans: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

    Joy, Gau, Castellucci, Prywes, Roy: "The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms." dans: The Journal of biological chemistry, Vol. 292, Issue 28, pp. 11777-11791, (2017) (PubMed).

    Yang, Liu, Jiang, Wang, Zhang: "Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model." dans: Frontiers in pharmacology, Vol. 8, pp. 44, (2017) (PubMed).

    Shen, Wu, Liu, Zhao, Zhao: "Epigallocatechin-3-gallate alleviates paraquat-induced acute lung injury and inhibits upregulation of toll-like receptors." dans: Life sciences, Vol. 170, pp. 25-32, (2016) (PubMed).

    Qian, Zhang, Hu, Xu, Chen, Hu, Zhao, Liu: "Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status." dans: Biomaterials, Vol. 70, pp. 12-22, (2015) (PubMed).

    Duan, Liu, Liang, Yang, Xia, Wang, Chen, Yu: "Oestrogen receptor-mediated expression of Olfactomedin 4 regulates the progression of endometrial adenocarcinoma." dans: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 863-74, (2014) (PubMed).

    Tang, Chen, Liang, Rong, Yao, Yang, Wu: "Selective antegrade cerebral perfusion attenuating the TLR4/NF-?B pathway during deep hypothermia circulatory arrest in a pig model." dans: Cardiology, Vol. 128, Issue 3, pp. 243-50, (2014) (PubMed).

    Wang, Ma, Su: "NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells." dans: Biological trace element research, Vol. 153, Issue 1-3, pp. 403-10, (2013) (PubMed).

    Liu, Ji, Zhang, Tong, Pan, Liu, Zhang, Huang, Su, Willard, Zheng: "Nonenzymatic glycation of high-density lipoprotein impairs its anti-inflammatory effects in innate immunity." dans: Diabetes/metabolism research and reviews, Vol. 28, Issue 2, pp. 186-95, (2012) (PubMed).

    Zhou, Zhou, Wang, Mu, Wu, Guo, Zhang, Wu: "Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro." dans: Acta pharmacologica Sinica, Vol. 33, Issue 1, pp. 120-6, (2012) (PubMed).

  • Antigène

    Histone 3 (H3) (Histone H3 (H3))

    Autre désignation

    Histone H3

    Sujet

    Synonyms: Histone H3, H3.1, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FA, H3FL, H3FC, H3FB, H3FD, H3FI, H3FH, H3FK, H3FF, H3FJ, H3.2, HIST2H3A, HIST2H3C, HIST2H3D, H3F2, H3FM, H3.3, H3F3A, H3F3B, H3.3A, H3.3B, H3F3, PP781, H3.3C, H3F3C, H3.5, H3.1t, HIST3H3, H3FT

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    ID gène

    3020

    UniProt

    P84243
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