MDC1 anticorps (AA 31-130)
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- Antigène Voir toutes MDC1 Anticorps
- MDC1 (Mdc1 (MDC1))
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Épitope
- AA 31-130
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MDC1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MDC1
- Isotype
- IgG
- Top Product
- Discover our top product MDC1 Anticorps primaire
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anti-Mdc1 (MDC1) antibody
MDC1 Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 1-100) antibodyMDC1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Mdc1 (MDC1) (N-Term) antibodyMDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 unconjugated
anti-Mdc1 (MDC1) (N-Term) antibody (HRP)MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 HRP
anti-Mdc1 (MDC1) (N-Term) antibody (FITC)MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 FITC
anti-Mdc1 (MDC1) (N-Term) antibody (Alkaline Phosphatase (AP))MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 Alkaline Phosphatase (AP)
anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 Biotin
anti-Mdc1 (MDC1) (N-Term) antibody (PE)MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 PE
anti-Mdc1 (MDC1) (N-Term) antibody (APC)MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 APC
anti-Mdc1 (MDC1) (N-Term) antibody (PerCP)MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 PerCP
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MDC1 (Mdc1 (MDC1))
- Autre désignation
- MDC1 (MDC1 Produits)
- Synonymes
- anticorps 6820401C03, anticorps AA413496, anticorps Nfbd1, anticorps mKIAA0170, anticorps NFBD1, anticorps mediator of DNA damage checkpoint 1, anticorps mediator of DNA-damage checkpoint 1, anticorps Mdc1, anticorps MDC1
- Sujet
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Synonyms: NFBD1, Mediator of DNA damage checkpoint protein 1, Nuclear factor with BRCT domains 1, MDC1, KIAA0170
Background: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.
- ID gène
- 9656
- UniProt
- Q14676
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