P5CS anticorps (AA 35-204)

N° du produit ABIN7825260

Cet anticorps Lapin Polyclonal détecte spécifiquement P5CS dans IHC. Il présente une réactivité envers Poisson zèbre (Danio rerio).

Aperçu rapide pour P5CS anticorps (AA 35-204) (ABIN7825260)

Antigène: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P5CS est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-P5CS anticorps

Épitope: AA 35-204

Fonction: Anti-Zebrafish P5CS/ALDH18A1 Antibody

Attributs du produit: Anti-Zebrafish P5CS/ALDH18A1 Antibody catalog # AZA4IGC8. Tested in IHC applications. This antibody reacts with Zebrafish.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived zebrafish P5CS/ALDH18A1 recombinant protein (Position: R35-A204).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry, 2-5 μg/mL, Zebrafish

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur P5CS

Antigène: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Autre désignation: ALDH18A1

Sujet: Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene. This gene is mapped to 10q24.1. This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate,a critical step in the de novo biosynthesis of proline,ornithine and arginine. Mutations in this gene lead to hyperammonemia,hypoornithinemia,hypocitrullinemia,hypoargininemia and hypoprolinemia and may be associated with neurodegeneration,cataracts and connective tissue diseases. Alternatively spliced transcript variants,encoding different isoforms,have been described for this gene.