ATG5 anticorps (AA 118-155)

N° du produit ABIN7825269

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG5 dans IHC. Il présente une réactivité envers Poisson zèbre (Danio rerio).

Aperçu rapide pour ATG5 anticorps (AA 118-155) (ABIN7825269)

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG5 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-ATG5 anticorps

Épitope: AA 118-155

Fonction: Anti-Zebrafish ATG5 Antibody

Attributs du produit: Anti-Zebrafish ATG5 Antibody catalog # AZF1RDC0. Tested in IHC applications. This antibody reacts with Zebrafish.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived zebrafish ATG5 recombinant protein (Position: S118-L155).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry, 2-5 μg/mL, Zebrafish

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur ATG5

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Autre désignation: ATG5

Sujet: Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is also known as APG5 or ASP, and this gene is mapped to 6q21. It is found that knockdown of ATG5 in hepatocytes increased triglyceride levels with oleate or a second endogenous stimulus for triglyceride formation. These hepatocytes with ATG5 knockdown also had increased lipid droplet number and size. ATG5 is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.

ID gène: 494180

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy