CSF1R anticorps (AA 409-977)

N° du produit ABIN7825319

Cet anticorps anti-CSF1R Polyclonal Lapin (ABIN7825319) détecte spécifiquement CSF1R dans IHC. L’anticorps est réactif avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour CSF1R anticorps (AA 409-977) (ABIN7825319)

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSF1R est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-CSF1R anticorps

Épitope: AA 409-977

Fonction: Anti-Zebrafish M-CSFR/CSF1R Antibody

Attributs du produit: Anti-Zebrafish M-CSFR/CSF1R Antibody N6. Tested in IHC applications. This antibody reacts with Zebrafish.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived zebrafish M-CSFR/CSF1R recombinant protein (Position: D409-C977)

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry, 2-5 μg/mL, Zebrafish

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur CSF1R

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Autre désignation: CSF1R

Sujet: CSF1R(Colony-Stimulating Factor 1 Receptor) also known as MCSFR, FMS, c-FMS, CD115, ONCOGENE FMS or CD115 ANTIGEN, encodes a tyrosine kinase growth factor receptor for colony-stimulating factor-1, the macrophage-and monocyte-specific growth factor. The gene is located on long arm of chromosome 5(5q32) on the Crick(minus) strand. The as-yet-unidentified°CSF1 Rpromoter/enhancer sequences may be confined to the nucleotides separating the 2 genes or could potentially lie within the PDGFR gene itself. The encoded protein is a single pass type I membrane protein and acts as the receptor for°Colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. The encoded protein is atyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Kondo et al.(2000) showed that the endogenous myelomonocytic cytokine receptors for GM-CSF and macrophage colony-stimulating factor(CSF1R) are expressed at low to moderate levels on the more primitive hematopoietic stem cells, are absent on common lymphoid progenitors, and are upregulated after myeloid lineage induction by IL2.

UniProt: Q9I8N6

Pathways: Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization