CDK5 anticorps (AA 1-226)
Aperçu rapide pour CDK5 anticorps (AA 1-226) (ABIN7825326)
Antigène
Voir toutes CDK5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-226
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Fonction
- Anti-Zebrafish CDK5 Antibody
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Attributs du produit
- Anti-Zebrafish-CDK5-Antibody catalog # AZQ9DE44. Tested in WB applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived zebrafish CDK5 recombinant protein (Position: M1-Q226).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Zebrafish
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
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Autre désignation
- CDK5
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Sujet
- CDK5, Cyclin-Dependent Kinase5, is also known as PSSALRE. The p34(CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle.The PSSALRE expression is in all human tissues and cell lines tested.The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.
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Pathways
- Cycle Cellulaire, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
Antigène
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