LIN7C anticorps (AA 1-73)

N° du produit ABIN7825506

Cet anticorps Lapin Polyclonal détecte spécifiquement LIN7C dans WB. Il présente une réactivité envers Poisson zèbre (Danio rerio).

Aperçu rapide pour LIN7C anticorps (AA 1-73) (ABIN7825506)

Antigène: LIN7C (Lin-7 Homolog C (LIN7C))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN7C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LIN7C anticorps

Épitope: AA 1-73

Fonction: Anti-Zebrafish LIN7C Antibody

Attributs du produit: Anti-Zebrafish LIN7C Antibody catalog #AZQ66IB0. Tested in WB applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived zebrafish LIN7C recombinant protein (Position: M1-A73)

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Zebrafish

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur LIN7C

Antigène: LIN7C (Lin-7 Homolog C (LIN7C))

Autre désignation: LIN7C

Sujet: Lin-7 homolog C is a protein that in humans is encoded by the LIN7C gene. LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Pathways: Synaptic Membrane