PAM anticorps (AA 69-914)

N° du produit ABIN7825666

L’anticorps anti-PAM Polyclonal Lapin est utilisé pour la détection de PAM dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et FACS.

Aperçu rapide pour PAM anticorps (AA 69-914) (ABIN7825666)

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-PAM anticorps

Épitope: AA 69-914

Fonction: Anti-PAM Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PAM shares 97.4% amino acid (aa) sequence identity with mouse PAM.

Attributs du produit: Anti-PAM Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PAM recombinant protein (Position: K69-R914). Human PAM shares 97.4% amino acid (aa) sequence identity with mouse PAM.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PAM

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Autre désignation: PAM

Sujet:

Background: This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Gene Full Name: peptidylglycine alpha-amidating monooxygenase

Poids moléculaire: 120 kDa

ID gène: 5066

UniProt: P19021