Dysferlin anticorps (AA 1901-2119) (Biotin)

N° du produit ABIN740147

L’anticorps Lapin Polyclonal anti-Dysferlin a été validé pour ELISA. Il convient pour détecter Dysferlin dans des échantillons de Humain.

Aperçu rapide pour Dysferlin anticorps (AA 1901-2119) (Biotin) (ABIN740147)

Antigène: Dysferlin (DYSF)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dysferlin est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-Dysferlin anticorps (Biotin)

Épitope: AA 1901-2119

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DYSF

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Dysferlin

Antigène: Dysferlin (DYSF)

Autre désignation: Dysferlin

Sujet:

Synonyms: DMAT, DYSF, Dysferlin Dystrophy associated fer 1 like protein Fer 1 like protein 1, Dysferlin limb girdle muscular dystrophy 2B autosomal recessive, Dysferlin limb girdle muscular dystrophy 2B, Dystrophy associated fer 1 like 1, Dystrophy associated fer 1 like protein, Dystrophy associated fer1 like 1, Dystrophy associated fer1 like protein, Fer 1 like protein 1, Fer1 like protein 1, FER1L1, FLJ00175, FLJ90168, LGMD 2B, LGMD2B, Limb girdle muscular dystrophy 2B autosomal recessive , Limb girdle muscular dystrophy 2B, Miyoshi myopathy, MM, DYSF_HUMAN.

Background: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008].

ID gène: 8291

UniProt: O75923