Recombinant Aconitase 1 anticorps
Aperçu rapide pour Recombinant Aconitase 1 anticorps (ABIN7827991)
Antigène
Voir toutes Aconitase 1 (ACO1) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant Aconitase 1/ACO1 Monoclonal Antibody
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Purification
- Protein A purified
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Immunogène
- Recombinant human Aconitase 1/ACO1 fragment
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- Aconitase 1 (ACO1)
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Autre désignation
- Aconitase 1/ACO1
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Sujet
- HEL,IRP,ACO,IREB,ACO1,ACONS,HEL60,IREB1,IREBP,IREBP1,IRP1,ACO 1,ACOC,Aconitase,Aconitase 1 soluble,Aconitase1,Aconitate hydratase,Citrate hydro lyase,Citrate hydro-lyase,Cytoplasmic aconitate hydratase,Ferritin repressor protein,IRE BP 1,IREB 1,IRE-BP 1,Iron regulatory protein 1,Iron responsive element binding protein 1,Iron-responsive element-binding protein 1,IRP 1,OTTHUMP00000045233,Aconitase 1 is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 98 kDa
Observed MW: 105 kDa The actual band is not consistent with the expectation.
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UniProt
- P21399
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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