Recombinant ACE2 anticorps

N° du produit ABIN7828021

Cet anticorps Lapin Monoclonal détecte spécifiquement ACE2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant ACE2 anticorps (ABIN7828021)

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ACE2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A708

Détail du produit anti-ACE2 anticorps

Fonction: Recombinant ACE2 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000,IHC 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur ACE2

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Autre désignation: ACE2

Sujet: ACE,UNQ,PRO,Metalloprotease MPROT,Angiotensin-converting enzyme,ACE2,ACEH,ACEII,Angiotensin-converting enzyme 2,Angiotensin-converting enzyme homolog,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15,Processed angioten,UNQ868,PRO1885,ACEH,angiotensin-converting enzyme 2,ACE 2,ACE related carboxypeptidase,Angiotensin converting enzyme 2,Angiotensin converting enzyme homolog,Angiotensin converting enzyme like protein,Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2,Angiotensin I converting enzyme 2,DKFZP434A014,EC 3.4.17,metalloprotease MPROT 15,OTTHUMP00000022963,Processed angiotensin-converting enzyme 2,ACE2 is a carboxypeptidase that catalyses the conversion of angiotensin I to angiotensin 1-9, or of angiotensin II to the vasodilator angiotensin 1-7. ACE2 is a critical component in the renin-angiotensin system (RAS). ACE2 is predominantly expressed in vascular endothelial cells of the heart and kidney and Leydig and Sertoli cells of the testis. The unique expression pattern of ACE2 determines its essential role in the regulation of cardiovascular and kidney functions, as well as fertility. ACE2 protein is localized mainly in the extracellular space with its carboxy-terminal end attached to the membrane via its transmembrane domain. Active ACE2 enzyme is secreted by cleavage at the amino terminus. Research studies have shown that ACE2 expression is elevated in human failing heart. ACE2 has also been identified as the receptor for SARS and SARS-CoV-2 coronaviruses. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 92 kDa

Observed MW: 100, 120 kDa The actual band is not consistent with the expectation.

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour