Recombinant CEACAM6 anticorps
Aperçu rapide pour Recombinant CEACAM6 anticorps (ABIN7828064)
Antigène
Voir toutes CEACAM6 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant CEACAM6 Monoclonal Antibody
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Purification
- Protein A purified
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:1000,IHC 1:200
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
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Autre désignation
- CEACAM6
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Sujet
- CEACAM,CEACAM6,CD66c,CEAL,NCA,Carcinoembryonic antigen related cell adhesion molecule 6,Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen),Carcinoembryonic antigen-related cell adhesion molecule 6,CD 66c,CD66c antigen,CEA LIKE PROTEIN,CEACAM 6,CEAM6,MGC93832,Non specific cross reacting antigen,Non-specific crossreacting antigen,Normal cross reacting antigen,Normal cross-reacting antigen,Carcinoembryonic antigen (CEA)-related cell adhesion molecule 6 (CEACAM6) is a member of the CEA-related cell adhesion molecule (CEACAM) family. CEACAMs bind to themselves and other family members to carry out numerous cellular functions, including proliferation, signaling, differentiation, tumor suppression, and survival. CEACAM6 is a single-chain, glycosylphosphatidylinositol (GPI)-anchored, highly glycosylated protein that is normally expressed on epithelial cells and granulocytes. CEACAM6 mediates homophilic and heterophilic cell adhesion with other CEA-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils, and plays a role in neutrophil adhesion to cytokine-activated endothelial cells. High levels of CEACAM6 expression are also observed in several different cancers. In cancer, CEACAM6 promotes tumor progression, migration, invasion, and metastasis, and therefore is considered a target for therapeutic intervention. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 37 kDa
Observed MW: 40-100 kDa The actual band is not consistent with the expectation.
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UniProt
- P40199
Antigène
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