Recombinant CD70 anticorps
Aperçu rapide pour Recombinant CD70 anticorps (ABIN7828092)
Antigène
Voir toutes CD70 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant CD70 Monoclonal Antibody
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Purification
- Protein A purified
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Immunogène
- Recombinant human CD70 fragment
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:500-1:1000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- CD70 (CD70 Molecule (CD70))
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Autre désignation
- CD70
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Sujet
- Tumor necrosis factor ligand superfamily member,TNFSF,CD70,CD27-L,CD27L,CD27LG,TNFSF7,TNLG8A,CD27 ligand,CD70 antigen,Tumor necrosis factor ligand superfamily member 7,Ki-24,CD27L,TNFSF7,CD 27L,CD 70,CD27 L,CD27 LG,CD70 Molecule,Ki 24 antigen,Ki24 antigen,member 7,sCD27 Ligand,soluble CD27 Ligand,Surface antigen CD70,TNFSF 7,Tumor necrosis factor (ligand) superfamily,CD70 is a type II transmembrane glycoprotein and a member of the tumor necrosis factor ligand superfamily (TNFSF), also known as CD27L and TNFSF7. It is normally expressed on medullary thymic epithelial cells. Its expression is induced on activated lymphoid cells (B cells, T cells, and NK cells) and dendritic cells. CD70 is a ligand for CD27, a co-stimulatory receptor that plays an important role in T cell activation and proliferation. CD70 overexpression has been reported in various tumors such as renal cell carcinoma, glioblastoma, and non-small cell lung carcinoma and it's being actively pursued as a therapeutic target. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 23 kDa
Observed MW: 27,54,81 kDa The actual band is not consistent with the expectation.
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UniProt
- P32970
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Pathways
- Cancer Immune Checkpoints
Antigène
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