Recombinant CBX4 anticorps

N° du produit ABIN7828111

Cet anticorps Lapin Monoclonal détecte spécifiquement CBX4 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant CBX4 anticorps (ABIN7828111)

Antigène: CBX4 (Chromobox Homolog 4 (CBX4))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CBX4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A527

Détail du produit anti-CBX4 anticorps

Fonction: Recombinant CBX4 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human CBX4 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB(human) 1:500-1:1000,WB(rat) 1:1000-1:5000,IHC 1:200-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CBX4

Antigène: CBX4 (Chromobox Homolog 4 (CBX4))

Autre désignation: CBX4

Sujet: Cbx,CBX4,CBX4 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. CBX4 itself is a SUMO E3 ligase, and its function influences EMT, DNA damage response, tumor angiogenesis, and self-renewal. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is involved in the SUMOylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 61 kDa

Observed MW: 61 kDa

UniProt: O00257