Recombinant CHD4 anticorps

N° du produit ABIN7828114

Cet anticorps Lapin Monoclonal détecte spécifiquement CHD4 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant CHD4 anticorps (ABIN7828114)

Antigène: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CHD4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A649

Détail du produit anti-CHD4 anticorps

Fonction: Recombinant CHD4 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human CHD4 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000-3000,IHC 1:50-100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CHD4

Antigène: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Autre désignation: CHD4

Sujet: CHD,CHD4,CHD-4,Mi-2b,Mi2-BETA,SIHIWES,Chromodomain helicase DNA-binding protein 4 (CHD4) is an ATP dependent chromatin remodeler and a major subunit of the repressive NuRD complex. This complex plays key roles in transcriptional regulation and reorganization and maintenance of chromatin structure, as it targets pericentromeric heterochromatin and has recently been implicated in DNA damage repair, being rapidly recruited to DNA double strand breaks. CHD4 is a novel BRIT1 binding partner that regulates the HR repair process, which is a critical pathway of repairing DNA double strand breaks and plays an essential role in maintaining genomic integrity. The calculated molecular weight of CHD4 is 218 kDa, but modified CHD4 is about 250-280 kDa. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 218 kDa

Observed MW: 280 kDa The actual band is not consistent with the expectation.

UniProt: Q14839