Recombinant COPS3 anticorps

N° du produit ABIN7828134

Cet anticorps anti-COPS3 Monoclonal Lapin (Clone A192) (ABIN7828134) détecte spécifiquement COPS3 dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant COPS3 anticorps (ABIN7828134)

Antigène: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp COPS3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A192

Détail du produit anti-COPS3 anticorps

Fonction: Recombinant COPS3 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human COPS3 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur COPS3

Antigène: COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))

Autre désignation: COPS3

Sujet: SGN,Csn,COPS,COPS3,CSN3,SGN3,Constitutive photomorphogenic homolog subunit 3,COP 9 (constitutive photomorphogenic) subunit 3,COP 9 complex homolog subunit 3,COP 9 complex S3,COP 9 complex subunit 3,COP 9 constitutive photomorphogenic homolog subunit 3,COP 9 homolog,COP 9 signalosome complex subunit 3,COP 9 signalosome subunit 3,COP 9 subunit 3,COP9 (constitutive photomorphogenic) subunit 3,COP9 complex homolog subunit 3,COP9 complex S3,COP9 complex subunit 3,COP9 constitutive photomorphogenic homolog subunit 3,COP9 homolog,COP9 signalosome complex subunit 3,COP9 signalosome subunit 3,COP9 subunit 3,COPS 3,CSN 3,JAB 1 containing signalosome subunit 3,JAB1 containing signalosome subunit 3,JAB1-containing signalosome subunit 3,SGN 3,Signalosome subunit 3,Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 44 kDa

Observed MW: 44 kDa

UniProt: Q9UNS2

Pathways: Cycle Cellulaire