Recombinant EIF3B anticorps

N° du produit ABIN7828188

Cet anticorps anti-EIF3B Monoclonal Lapin (Clone A212) (ABIN7828188) détecte spécifiquement EIF3B dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant EIF3B anticorps (ABIN7828188)

Antigène: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF3B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A212

Détail du produit anti-EIF3B anticorps

Fonction: Recombinant eIF3B Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human eIF3B1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur EIF3B

Antigène: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Autre désignation: eIF3B

Sujet: PRT,EIF3S,EIF3B,EIF3-ETA,EIF3-P110,EIF3-P116,EIF3S9,PRT1,RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2: GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. UniRule annotation4 Publications (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 92 kDa

Observed MW: 116 kDa The actual band is not consistent with the expectation.

UniProt: P55884

Pathways: Ribonucleoprotein Complex Subunit Organization