Recombinant Gelsolin anticorps

N° du produit ABIN7828221

Cet anticorps anti-Gelsolin Monoclonal Lapin (Clone A612) (ABIN7828221) détecte spécifiquement Gelsolin dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant Gelsolin anticorps (ABIN7828221)

Antigène: Gelsolin (GSN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Gelsolin est non-conjugé

Application: Western Blotting (WB)

Clone: A612

Détail du produit anti-Gelsolin anticorps

Fonction: Recombinant Gelsolin Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Gelsolin fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:100-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Gelsolin

Antigène: Gelsolin (GSN)

Autre désignation: Gelsolin

Sujet: DKFZp313L,GSN,ADF,AGEL,gelsolin,Actin depolymerizing factor,DKFZp313L0718,Brevin,GELS,Actin-depolymerizing factor,Actin-depolymerizing factor,ADF,AGEL,Brevin,GELS,GSN,Gelsolin also named as actin-depolymerizing factor, ADF, AGEL or Brevin, is an 83 kDa protein that shares structural and functional homology to villin and adseverin/scinderin. Gelsolin plays an important role in actin filament assembly by capping and severing actin proteins in a Ca2+-dependent manner. Gelsolin is important for cellular events (e.g., membrane ruffling, chemotaxis, ciliogenesis) that require cytoskeletal remodeling. Accordingly, cells from gelsolin knockout mice exhibit motility defects, including a failure to ruffle in response to growth factor stimulation. In humans, defects in gelsolin have been linked to amyloidosis type 5 (AMYL5), a hereditary disease characterized by cranial neuropathy, which appears to result from gelsolin amyloid deposition. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 85 kDa

Observed MW: 82 kDa The actual band is not consistent with the expectation.

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy