Recombinant Glutamate Receptor 3 anticorps
Aperçu rapide pour Recombinant Glutamate Receptor 3 anticorps (ABIN7828228)
Antigène
Voir toutes Glutamate Receptor 3 (GRIA3) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant Glutamate receptor 3 Monoclonal Antibody
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Purification
- Protein A purified
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Immunogène
- Recombinant human Glutamate receptor 3 fragment
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Isotype
- IgG, kappa
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Indications d'application
- WB 1:1000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Date de péremption
- 12 months
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- Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))
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Autre désignation
- Glutamate receptor 3
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Sujet
- MRX,GRIA,GLUR,GluA,GLUR-K,GRIA3,GLUR-C,GLUR-K3,GLUR3,GLURC,GluA3,MRX94,AMPA 3,AMPA selective glutamate receptor 3,AMPA-selective glutamate receptor 3,dJ1171F9.1,GLUK3,GluR 3,GLUR C,GLUR K3,GluR-3,Glutamate ionotropic receptor AMPA type subunit 3,Glutamate receptor,Glutamate receptor 3,Glutamate receptor C,Glutamate receptor ionotrophic AMPA 3,Glutamate receptor ionotropic,Glutamate receptor subunit 3,GRIA 3,Ionotrophic Glutamate Receptor,ionotropic,AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Glutamate receptor 3 (GluR3) knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission. Aberrant GluR3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Rett's syndrome, amyotrophic lateral sclerosis and Alzheimer disease. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Poids moléculaire
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Calculated MW: 101 kDa
Observed MW: 101 kDa
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UniProt
- P42263
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Pathways
- Signalisation PI3K-Akt, cAMP Metabolic Process, Synaptic Membrane
Antigène
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